GNA15

AliasesGNA15, GNA16, G protein subunit alpha 15, HG1L

External IDsOMIM: 139314; MGI: 95770; HomoloGene: 1563; GeneCards: GNA15; OMA:GNA15 - orthologs

Chr.Chromosome 19 (human)^[1]

End3,163,749 bp^[1]

GNA15
Identifiers
Aliases	GNA15, GNA16, G protein subunit alpha 15, HG1L
External IDs	OMIM: 139314; MGI: 95770; HomoloGene: 1563; GeneCards: GNA15; OMA:GNA15 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.3 Start 3,136,033 bp[1] End 3,163,749 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 C1|10 39.72 cM Start 81,338,140 bp[2] End 81,360,059 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva gingival epithelium monocyte oral cavity skin of abdomen buccal mucosa cell amniotic fluid skin of leg olfactory zone of nasal mucosa periodontal fiber Top expressed in granulocyte lip esophagus embryo transitional epithelium of urinary bladder embryo morula blastocyst zone of skin stroma of bone marrow More reference expression data BioGPS n/a
Gene ontology Molecular function guanyl nucleotide binding nucleotide binding GTP binding metal ion binding GTPase activity G-protein beta/gamma-subunit complex binding G protein-coupled receptor binding signal transducer activity Cellular component plasma membrane heterotrimeric G-protein complex Biological process platelet activation phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway phospholipase C-activating dopamine receptor signaling pathway activation of phospholipase C activity signal transduction adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2769 14676 Ensembl ENSG00000060558 ENSMUSG00000034792 UniProt P30679 P30678 RefSeq (mRNA) NM_002068 NM_010304 RefSeq (protein) NP_002059 NP_034434 Location (UCSC) Chr 19: 3.14 – 3.16 Mb Chr 10: 81.34 – 81.36 Mb PubMed search [3] [4]
Wikidata
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Guanine nucleotide-binding protein subunit alpha-15 is a protein that in humans is encoded by the GNA15 gene.^[5][6][7] G₁₅α is a member of the Gq alpha subunit family, and functions as a constituent of a heterotrimeric G protein in cell signal transduction. It was also previously known as G₁₆α.^[5]