GR-159897

GR-159897
Identifiers
	IUPAC name 5-fluoro-3-(2-(4-methoxy-4-([(R)-phenylsulphinyl]methyl)-1-piperidinyl)ethyl)-1H-indole;
CAS Number	158848-32-9 ;
PubChem CID	9555764;
ChemSpider	2807862;
CompTox Dashboard (EPA)	DTXSID20393749 ;
Chemical and physical data
Formula	C23H27FN2O2S
Molar mass	414.54 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c4ccccc4S(=O)CC2(OC)CCN(CC2)CCc(c1cc3F)c[nH]c1cc3;
	InChI InChI=1S/C23H27FN2O2S/c1-28-23(17-29(27)20-5-3-2-4-6-20)10-13-26(14-11-23)12-9-18-16-25-22-8-7-19(24)15-21(18)22/h2-8,15-16,25H,9-14,17H2,1H3; Key:BANYJBHWTOJQDU-UHFFFAOYSA-N;
	(verify)

GR-159897 is a potent and selective NK₂ receptor antagonist drug.^[1] It has anxiolytic effects in animal models,^[2] and also inhibits bronchoconstriction of the airways, which may potentially make it useful in the treatment of asthma.^[3]^[4]

CAS Number

158848-32-9^Y

PubChem CID

9555764

ChemSpider

2807862

CompTox Dashboard (EPA)

DTXSID20393749

Quick facts Identifiers, CAS Number ...

Close

[1]

[2]

[3]

[4]

GR-159897

See also

References

Related Articles

Identifiers

IUPAC name 5-fluoro-3-(2-(4-methoxy-4-([(R)-phenylsulphinyl]methyl)-1-piperidinyl)ethyl)-1H-indole
CAS Number	158848-32-9^Y
PubChem CID	9555764
ChemSpider	2807862
CompTox Dashboard (EPA)	DTXSID20393749
Chemical and physical data
Formula	C₂₃H₂₇FN₂O₂S
Molar mass	414.54 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c4ccccc4S(=O)CC2(OC)CCN(CC2)CCc(c1cc3F)c[nH]c1cc3
InChI InChI=1S/C23H27FN2O2S/c1-28-23(17-29(27)20-5-3-2-4-6-20)10-13-26(14-11-23)12-9-18-16-25-22-8-7-19(24)15-21(18)22/h2-8,15-16,25H,9-14,17H2,1H3 Key:BANYJBHWTOJQDU-UHFFFAOYSA-N
(verify)