GSK2881078

GSK2881078 is a drug which acts as a selective androgen receptor modulator (SARM). It was developed for the prevention of muscle wasting and sarcopenia in elderly people.^[1][2][3]

Legal status

• US: Investigational drug

CAS Number

• 1539314-06-1

PubChem CID

• 86709174

ChemSpider

• 57621607

Quick facts Legal status, Identifiers ...

GSK2881078

Legal status
Legal status	US: Investigational drug
Identifiers
IUPAC name 1-[(2R)-1-methylsulfonylpropan-2-yl]-4-(trifluoromethyl)indole-5-carbonitrile
CAS Number	1539314-06-1
PubChem CID	86709174
ChemSpider	57621607
UNII	47M5ZXU844
Chemical and physical data
Formula	C14H13F3N2O2S
Molar mass	330.33 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@H](CS(=O)(=O)C)N1C=CC2=C1C=CC(=C2C(F)(F)F)C#N
InChI InChI=1S/C14H13F3N2O2S/c1-9(8-22(2,20)21)19-6-5-11-12(19)4-3-10(7-18)13(11)14(15,16)17/h3-6,9H,8H2,1-2H3/t9-/m1/s1 Key:SKDVMPZQJMZEAC-SECBINFHSA-N

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In a phase II trial the drug was shown to be well tolerated and increased muscle strength in men with COPD.^[4]