Gary Ackers
American biochemist (1939–2011)
From Wikipedia, the free encyclopedia
Gary Keith Ackers (1939–2011)[1] was Emeritus Professor of Biochemistry and Molecular Biophysics of Washington University School of Medicine.
Gary Keith Ackers | |
|---|---|
| Born | 1939 |
| Died | 2011 (aged 71–72) |
| Known for | Agarose gel chromatography |
| Scientific career | |
| Fields | Thermodynamic linkage analysis of biological macromolecules, cooperative O2 binding to hemoglobin |
| Workplaces | Washington University in St. Louis |
His research focused on thermodynamic linkage analysis of biological macromolecules, addressing the molecular mechanism of cooperative O2 binding to human hemoglobin since the early 1970s. He was a Fellow of the Biophysical Society and one of the founders of the annual Gibbs Conference.[2]
Ackers invented agarose gel chromatography when he was a teenager. He went on the develop analytical gel chromatography methods for determinations of many important characteristics of water-soluble proteins; diffusion coefficient, molecular size,[3][4] thermodynamics of protein-protein interactions including important changes due to single amino acid substitutions.[5]