Wikiwand AI

Gem-associated protein 6

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Gem-associated protein 6 is a protein that in humans is encoded by the GEMIN6 gene.[5][6] The gem-associated proteins are those found in the gems of Cajal bodies.

AliasesGEMIN6, gem nuclear organelle associated protein 6
PDBOrtholog search: PDBe RCSB
Quick facts GEMIN6, Identifiers ...
GEMIN6
Identifiers
AliasesGEMIN6, gem nuclear organelle associated protein 6
External IDsOMIM: 607006; MGI: 1914492; GeneCards: GEMIN6
Available structures
PDBOrtholog search: PDBe RCSB
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024775

NM_026053
NM_001355458

RefSeq (protein)

NP_079051

NP_080329
NP_001342387

Location (UCSC)Chr 2: 38.75 – 38.79 MbChr 17: 80.53 – 80.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

GEMIN6 is part of a large macromolecular complex, the SMN localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM][6]

Interactions

Gem-associated protein 6 has been shown to interact with gem-associated protein 7.[7][8]

References

Further reading

Related Articles

Timelines

Top Qs

Fact Checks