Geodin
From Wikipedia, the free encyclopedia
Geodin
Names
IUPAC name
Methyl (2
R )-5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate
[ 1]
Other names
Identifiers
ChEBI
ChEMBL
ChemSpider
UNII
InChI=1S/C17H12Cl2O7/c1-6-11(18)13(21)10-14(12(6)19)26-17(15(10)22)8(16(23)25-3)4-7(20)5-9(17)24-2/h4-5,21H,1-3H3/t17-/m1/s1
Key: LUBKKVGXMXTXOZ-QGZVFWFLSA-N
CC1=C(C(=C2C(=C1Cl)O[C@]3(C2=O)C(=CC(=O)C=C3OC)C(=O)OC)O)Cl
Properties
C 17 H 12 Cl 2 O 7
Molar mass
399.18 g·mol−1
Except where otherwise noted, data are given for materials in their
standard state (at 25
°C [77
°F], 100
kPa).
Chemical compound
Geodin is an antibiotic against Gram-positive bacteria with the molecular formula C17 H8 Cl2 O7 .[ 1] [ 2] Geodin is produced by the fungus Aspergillus terreus .[ 3] [ 4]
1 2 "Geodin" . Pubchem.ncbi.NLM.nih.gov .
↑ Korzybski, Tadeusz; Kowszyk-Gindifer, Zuzanna; Kurylowicz, Wlodzimierz (3 September 2013). Antibiotics: Origin, Nature and Properties . Elsevier. p. 1291. ISBN 978-1-4832-2304-9 .
↑ Rønnest, Mads H.; Nielsen, Morten T.; Leber, Blanka; Mortensen, Uffe H.; Krämer, Alwin; Clausen, Mads H.; Larsen, Thomas O.; Harris, Pernille (15 March 2011). "(+)-Geodin from Aspergillus terreus" . Acta Crystallographica Section C Crystal Structure Communications . 67 (3): o125 – o128 . Bibcode :2011AcCrC..67O.125R . doi :10.1107/S0108270111005816 . PMID 21368412 .
↑ Gottlieb, David; Shaw, Paul D. (14 December 2013). Biosynthesis . Springer. p. 96. ISBN 978-3-662-38441-1 .
Vaidyanathan, Seetharaman; Harrigan, George G.; Goodacre, Royston (20 March 2006). Metabolome Analyses:: Strategies for Systems Biology . Springer Science & Business Media. p. 377. ISBN 978-0-387-25240-7 .
Comprehensive Natural Products III . Elsevier. 22 July 2020. p. 299. ISBN 978-0-08-102691-5 .