George Howard, 6th Earl of Carlisle

On 21 March 1801, Lord Carlisle was married to Lady Georgiana Cavendish (1783–1858), daughter of William Cavendish, 5th Duke of Devonshire and Lady Georgiana Spencer (the eldest daughter of John Spencer, 1st Earl Spencer).^[1] They were parents of twelve children:^[1]

1. George Howard, 7th Earl of Carlisle (1802–1864), who did not marry.
2. Lady Caroline Georgiana Howard (1803–1881), who married William Lascelles, Comptroller of the Household.
3. Lady Georgiana Howard (1804–1860), who married George Agar-Ellis, 1st Baron Dover.
4. Hon. Frederick George Howard (1805–1834), who died unmarried before his father.
5. Lady Harriet Elizabeth Georgiana Howard (1806–1868), who married George Sutherland-Leveson-Gower, 2nd Duke of Sutherland.
6. William George Howard, 8th Earl of Carlisle (1808–1889), who did not marry.
7. Edward Granville George Howard, 1st Baron Lanerton (1809–1880), who married Diana Ponsonby, daughter of the Hon. George Ponsonby.
8. Lady Blanche Georgiana Howard (1812–1840), who married William Cavendish, later Earl of Burlington and Duke of Devonshire.
9. Hon. Charles Wentworth George Howard (1814–1879), who married Mary Parke, daughter of James Parke, Baron Wensleydale. They were parents of George Howard, 9th Earl of Carlisle.
10. Lady Elizabeth Dorothy Anne Howard (1816–1891), who married Rev. Francis Richard Grey, son of Charles Grey, 2nd Earl Grey.
11. Hon. Henry George Howard (1818–1879), who married Mary Wellesley McTavish in 1845 at the house of her aunt, the Marchioness Wellesley. Mary was the daughter of John McTavish, British Consul at Baltimore, and Emily Caton (daughter of Richard Caton and granddaughter of Charles Carroll of Carrollton). He served as Secretary of the British Embassy in Paris. His wife died in Paris 21 February 1850, in her 23rd year.^[11]
12. Lady Mary Matilda Georgiana Howard (1823–1892), who married Henry Labouchere, 1st Baron Taunton.

Lord Carlisle died at Castle Howard, Yorkshire, in October 1848, aged 75, and was succeeded in the earldom by his eldest son, George. The Countess of Carlisle died at Castle Howard in August 1858, aged 75.

As his eldest son died unmarried and without legitimate issue, his third son became the 8th Earl of Carlisle in 1864. He also died unmarried and without legitimate issue, so the 9th Earl of Carlisle was his grandson, George James Howard, the only son of his fifth son Charles, whose descendants hold the titles to this day.

• Hansard 1803–2005: contributions in Parliament by the Earl of Carlisle
• "Howard, George (1773-1848)" . Dictionary of National Biography. London: Smith, Elder & Co. 1885–1900.