George and Cecil

They are complete opposites, but a perfect match. George and Cecil marks the first on screen team up of newlyweds Ryan Agoncillo and Judy Ann Santos-Agoncillo. This romantic comedy series follows the married life of policewoman George and school teacher Cecil. She does the dirty job, he does the house cleaning. She has a tough core, while he has the soft spot. Can this unconventional couple make their relationship work? See how George and Cecil overcome the challenges of marital life plus the issues of the people around them.

Judy Ann Santos portrays Georgina ‘George’ Castro-Murillo.

Ryan Agoncillo portrays Cecilio ‘Cecil’ Murillo.

• Judy Ann Santos as Georgina ‘George’ Castro-Murillo - the tough and rational wife of Cecil.
• Ryan Agoncillo as Cecilio ‘Cecil’ Murillo - the sensitive and emotional husband of George.

• Gladys Reyes as Miriam Macabanta - the policewoman best Friend of Georgina / George
• Christopher Roxas as Oscar Macabanta - the unemployed and philandering husband of Miriam.
• Tessie Tomas as Maribel Murillo - the image-conscious mother of Cecil. She finds it hard to deal with George's job as a cop.
• Al Tantay as Damian Castro - the disciplinarian father of George who disapproves of Cecil.
• Malou De Guzman as Ched Castro - the ‘drama queen’ mother of George.
• Dimples Romana as Charlie Castro - the sister of George. A single mother, Charlie is the seemingly hopeless daughter of Damian.
• Ynna Asistio as Diane Castro - the youngest sister of George.
• Dino Imperial as Tereso ‘Jun’ Murillo -the ‘gimikero’ and playboy younger brother of Cecil.
• Cacai Bautista as Ellen
• Archie Alemania as Ronnie Palacios - a close friend of George and Cecil. Ronnie feels insecure toward his financially successful wife.
• Dionne Monsanto as Grace Palacios - a successful career woman and wife of Ronnie.
• Cherrylou as Myra - Cecil's co-teacher
• Manuel Chua as Jojo Samortin
• Jommy Teotico as Gordon Trico
• Marion Dela Cruz as Paul Hermosa
• Enrique Gil as Carlo Barredo
• Adrian Solomon (replaced by Bugoy Cariño) as Toby Castro - son of Charlie Castro(Dimples Romana), the newest addition to the cast

• Ariel Ureta as Tereso Murillo Sr.
• Jessy Mendiola as Irene - Jun's ex-girlfriend
• Maricar Reyes as Kristina "Krissy"- Cecil's ex-girlfriend
• Zoren Legaspi as Epoy Montalban
• John James Uy as Dr. Menesses
• Vhong Navarro as Marco Reyes- George's ex-boyfriend
• Ella Cruz as Melissa Quezon
• Sergio Garcia as Damian Castro Jr. George's half-brother
• Regine Angeles