Marchetti has worked in football since the 1980s.[1] He became general secretary of the Lega Nazionale Professionisti in 1997, and oversaw new transfer systems, calendars, and licensing in Italy.[1]
In 2003, he was appointed marking director of UEFA, becoming the first Italian to hold the position when he assumed the position in 2004.[1][4] He went on to become UEFA director of competitions.[1][3]
In 2016, Marchetti entered the public eye when he became the main draw conductor for the UEFA Champions League, after his predecessor Gianni Infantino was elected president of FIFA.[3] Since then, he has developed what observers have called "a cult following" on social media,[5] and is known for his "unflappable" demeanor during the draws.[2]
In 2020, as director of competitions for UEFA, he was responsible for proposing alternative formats for the Champions League and Europa League seasons, in light of the global coronavirus pandemic.[6] In December 2021, he apologised publicly after technical errors required him to order the UEFA Champions League Round of 16 draw to be completely redrawn.[7][2]