Glucokinase regulator

GCKR
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4PXS, 4BBA, 4MQU, 4OLH, 4MSU, 4BB9, 4OHP, 4OP1, 4OP3, 4OHM, 4OHO, 4MRO, 4PX2, 4PX3, 4PX5, 4OHK, 4LY9, 4OP2
Identifiers
Aliases	GCKR, FGQTL5, GKRP, glucokinase (hexokinase 4) regulator, glucokinase regulator, fructose swodkoreceptor
External IDs	OMIM: 600842; MGI: 1096345; HomoloGene: 1139; GeneCards: GCKR; OMA:GCKR - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	27,523,684 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	31,484,658 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; left adrenal cortex; ; right adrenal gland; ; left ovary; ; right adrenal cortex; ; right ovary; ; pancreatic ductal cell; ; gastric mucosa; ; gonad; ; body of stomach;
	Top expressed in
	left lobe of liver; ; neural layer of retina; ; right lobe of liver; ; zygote; ; primary oocyte; ; pineal gland; ; ciliary body; ; embryo; ; secondary oocyte; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; fructose-6-phosphate binding; carbohydrate derivative binding; enzyme inhibitor activity; enzyme binding; carbohydrate binding;
Cellular component	nucleoplasm; nucleus; cytosol; cytoplasm; mitochondrion;
Biological process	negative regulation of glucokinase activity; response to fructose; triglyceride homeostasis; urate metabolic process; carbohydrate derivative metabolic process; regulation of glycolytic process; carbohydrate metabolic process; glucose homeostasis; protein import into nucleus;
	Sources:Amigo / QuickGO
Orthologs
	2646
	231103
	ENSG00000084734
	ENSMUSG00000059434
	Q14397
	Q91X44
	NM_001486
	NM_144909; NM_001374741
	NP_001477
	NP_659158; NP_001361670
	Wikidata
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