Glycine transaminase
From Wikipedia, the free encyclopedia
Glycine transaminase (EC 2.6.1.4) is an enzyme characterised from liver that catalyzes a reversible chemical reaction to interconvert glycine and α-ketoglutaric acid with glycolic acid and L-glutamic acid:[1][2]
Although reversible, the reaction strongly favours the synthesis of glycine.[3] This enzyme is a transferase, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is glycine:2-oxoglutarate aminotransferase. Other names in common use include glutamic-glyoxylic transaminase, glycine aminotransferase, glyoxylate-glutamic transaminase, L-glutamate:glyoxylate aminotransferase, and glyoxylate-glutamate aminotransferase. It employs one cofactor, pyridoxal phosphate.[4]
