Greek National Road 16
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| Εθνική Οδός 16 | ||||
 Route of the EO16 road, in blue | ||||
| Route information | ||||
| Existed | 9 July 1963–present | |||
| Major junctions | ||||
| West end | Thessaloniki | |||
| East end | Ierissos | |||
| Location | ||||
| Country | Greece | |||
| Regions | Central Macedonia | |||
| Primary destinations |
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| Highway system | ||||
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Greek National Road 16 (Greek: Εθνική Οδός 16), abbreviated as the EO16, is a national road in northern Greece. It connects Thessaloniki with Ierissos in Chalkidiki. At its beginning in Thessaloniki, it forms the Georgikis Scholis Highway, with three lanes in each direction, passing through one of the city's main commercial districts.
