HLA-B73

Human leukocyte antigen serotype From Wikipedia, the free encyclopedia

HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)

major histocompatibility complex (human), class I, B73
Alleles B*7301
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*7301
Locus chr.6 6p21.31

Serotype

B*73:01 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*55:03.[3]

B73 serotype recognition of B*7301 allele-group gene products[4]
B*73B73 OtherSample
allele%%size (N)
73012269106

B*7301 frequencies

HLA B*7301 frequencies
freq
ref.Population(%)
[5]Parsi (Karachi, Pakistan)4.9
[5]United Arab Emirates2.0
[5]Italy2.0
[5]Seri (Sonora, Mexico)1.5
[5]Purépecha (Michoacán, Mexico)1.5
[5]Jews (Israel) (*2 studies)1.2
[5]Beti (Cameroon)1.1
[5]Casablanca (Morocco)0.9
[5]Tbilisi (Georgia)0.9
[5]Mossi (Burkina Faso)0.9
[5]Bulgaria0.9
[5]Sudanese0.8
[5]Tuva (Russia) (2)0.8
[5]Oman0.8
[5]Bamileke (Cameroon)0.6
[5]Pathan (Pakistan)0.5
[5]Khalkha (Mongolia)0.5
[5]Druse Arabs (Israel)0.5
[5]Baloch (Iran)0.5
[5]Manchester (England)0.5
[5]Algeria (1)0.5
[5]Turkey0.4
[5]Amman (Jordan)0.3
[5]Shona (Harare, Zimbabwe)0.2
[5]Republic of Macedonia0.2
[5]Nandi (Kenya)0.2
[5]Luo (Kenya)0.2
[5]Campania (Italy)0.2
[5]Greece0.2

References

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