HLA-DQ9

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HLA-DQ9
Illustration of HLA-DQ with bound peptide.
Polymer typeMHC Class II, DQ cell surface antigen
Cis-haplotype Haplotype
isoform subtype DQA1 DQB1
DQ α2β9 DQ9.2 *0201 *0303
DQ α3β9 DQ9.3 *0302 *0303

HLA-DQ9 (DQ9) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ9 is a split antigen of the DQ3 broad antigen. DQ9 is determined by the antibody recognition of β9 and this generally detects the gene product of DQB1*0303.

DQ2, DQ3, DQ7, DQ8, and DQ9 recognition of DRB1*0303 product[1]
DQ9 DQ3DQ2DQ7DQ8sample
 % % % % %(N)
*0303671211112563
Red indicates the level of 'false' reaction in non-DQ9 serotypes
Alleles link-out to IMGT/HLA Databease at EBI

The serotyping efficiency of DQ9 is poor. The recognition of DQB1*0303 by DQ9 and or DQ3 is poorest, DQ2 which recognizes a different DQB1 subgroup recognizes DQB1*0303 as efficiently as DQ3. For this reason DQ9 serotyping is a poor method of typing for transplantation or disease association prediction or study.

DQB1*0303

Haplotypes and disease

References

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