HOOK2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Protein Hook homolog 2 (HK2) is a protein[5] that in humans is encoded by the HOOK2 gene.[6][7]

AliasesHOOK2, HK2, hook microtubule-tethering protein 2, hook microtubule tethering protein 2
End12,872,740 bp[1]
Quick facts Identifiers, Aliases ...
HOOK2
Identifiers
AliasesHOOK2, HK2, hook microtubule-tethering protein 2, hook microtubule tethering protein 2
External IDsOMIM: 607824; MGI: 2181664; HomoloGene: 8332; GeneCards: HOOK2; OMA:HOOK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001100176
NM_013312

NM_001167991
NM_133255
NM_001363497
NM_001363498

RefSeq (protein)

NP_001093646
NP_037444

Location (UCSC)Chr 19: 12.76 – 12.87 MbChr 8: 84.99 – 85 Mb
PubMed search[3][4]
Wikidata
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Function

Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[7]

References

Further reading

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