HP1BP3

HP1BP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2RQP
Identifiers
Aliases	HP1BP3, HP1-BP74, HP1BP74, heterochromatin protein 1 binding protein 3
External IDs	OMIM: 616072; MGI: 109369; HomoloGene: 7774; GeneCards: HP1BP3; OMA:HP1BP3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	20,787,323 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	137,971,994 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; ventricular zone; ; tibia; ; trabecular bone; ; parietal pleura; ; visceral pleura; ; skin of hip; ; Achilles tendon; ; parotid gland; ; seminal vesicula;
	Top expressed in
	renal corpuscle; ; medullary collecting duct; ; ventricular zone; ; condyle; ; ascending aorta; ; aortic valve; ; neural layer of retina; ; ganglionic eminence; ; vestibular membrane of cochlear duct; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; nucleosome binding; protein binding; chromatin binding;
Cellular component	nucleosome; nucleus; chromosome; nuclear speck;
Biological process	regulation of nucleus size; nucleosome assembly; heterochromatin organization; regulation of transcription, DNA-templated; regulation of cell population proliferation; cellular response to hypoxia;
	Sources:Amigo / QuickGO
Orthologs
	50809
	15441
	ENSG00000127483
	ENSMUSG00000028759
	Q5SSJ5
	Q3TEA8
	NM_016287; NM_001372052
NM_001122896; NM_001122897; NM_001285478; NM_001285479; NM_001285480;
	NM_001285481; NM_010470; NM_001356431; NM_001356432
NP_057371; NP_001358981; NP_001363716; NP_001363717; NP_001363718;
	NP_001363719; NP_001363720; NP_001363721; NP_001363722; NP_001363723; NP_001363724; NP_001363725; NP_001363726
NP_001116368; NP_001116369; NP_001272407; NP_001272408; NP_001272409;
	NP_001272410; NP_034600; NP_001343360; NP_001343361
	Wikidata
View/Edit Human	View/Edit Mouse

Heterochromatin protein 1, binding protein 3 is a protein that in humans is encoded by the HP1BP3 gene.^[5] It has been identified as a novel subtype of the linker histone H1, involved in the structure of heterochromatin ^[6]^[7]^[8]