While in Finland, she worked for an arts and crafts business in Helsinki where she was trained by Uhra Simberg Ehrstrøm, a textile artist. She also attended evening courses with the Finnish designer Kaj Franck.[1]
On returning to Denmark in 1953, she was employed by Paula Trock at Spindegården in Askov. She opened her workshop in Aabenraa in 1955. In 1970, on taking over management of Spindegården, she moved the firm to Aabenraa where she produced textiles with traditional Danish designs, including carpets, curtains and upholstery. Her designs are simple but attractive, often with striped patterns with few colours. She has also developed knitted goods and other textiles in collaboration with other artists, including Vibeke Lind, Pia Hedegaard, Anne Abildtrup, Kirsten Toftegaard and Johanne Heide. Her naturally produced materials that could not be obtained elsewhere proved popular with those designing folk costumes.[1]
In the 1980s and 1990s, Vedel gained recognition for the textiles she created for decorating churches and cathedrals throughout the country. They have also been used to decorate courtrooms and company buildings at home and abroad.[1] In 1952, Finn Juhl used her materials for the upholstery and curtains when designing the United Nations Trusteeship Council in New York. They were reapplied in the 2013 renovation.[4]