Haplogroup M8

Human mitochondrial DNA haplogroup From Wikipedia, the free encyclopedia

In human mitochondrial genetics, Haplogroup M8 is a human mitochondrial DNA (mtDNA) haplogroup.[2][3]

Possible time of origin34,400 YBP[1]
Possible place of originEast Asia
AncestorM
DescendantsM8a, CZ
Quick facts Possible time of origin, Possible place of origin ...
Haplogroup M8
Possible time of origin34,400 YBP[1]
Possible place of originEast Asia
AncestorM
DescendantsM8a, CZ
Defining mutationsA4715G C7196a G8584A A15487t T16298C[1]
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Origin

Haplogroup M8 is a descendant of haplogroup M. Haplogroup M8 is divided into subclades M8a, C and Z.

Distribution

It is an East Asian haplogroup. Today, haplogroup M8 is found at its highest frequency in indigenous populations of East Siberia such as Evenk and Yukaghir. Haplogroup M8 is one of the most common mtDNA haplogroups among Yakut, Tuvan. Haplogroup C, the most major one of three subclades, is highly distributed among the Amerindian and Indigenous peoples of East Siberia. Haplogroup Z, another one of three subclades, is highly distributed among Even from Kamchatka (8/39 Z1a2a, 3/39 Z1a3, 11/39 = 28.2% Z total). mtDNA Haplogroup M8a, a not well known one of the three subclades, is highly distributed among Northern Han Chinese from Liaoning (16/317 = 5.0%).

Table of Frequencies by ethnic group

More information Population, Frequency ...
Population Frequency Count Source Subclades
Yakut0.407378Pakendorf 2006C=153, Z=1
Mongolian0.27747Jin 2009M8a=1, C=10, Z=2
Xibe (Xinjiang)0.145137[citation needed]C=13, Z=7
Han Chinese (Liaoning)0.120317[citation needed]M8a=16, C=14, Z=8
Korean (Chungcheong)0.103117[citation needed]-
Han Chinese (Shandong)0.099393[citation needed]M8a=8, C=14, Z=17
Han Chinese (Shanghai)0.09751[citation needed]M8a=7, C=5, Z=2
Han Chinese (Henan)0.086208[citation needed]M8a=9, C=7, Z=2
Korean (Gangwon)0.079114[citation needed]-
Manchurian0.07540Jin 2009M8a=1, C=1, Z=1
Korean (Gyeongsang)0.071112[citation needed]-
Korean (Seoul)0.067134[citation needed]-
Korean (Jeolla)0.059118[citation needed]-
Korean (Gwangju)0.03360[citation needed]M8a=2
Japanese0.0321312Tanaka 2004M8a=18, C=7, Z=17
Vietnamese0.02935[citation needed]-
Han Chinese (South)0.02678[citation needed]-
Korean (Jeju Island)0.009113[citation needed]-
Okinawan0.003326Umetsu 2005CZ=1
Taiwan Aboriginal0.000640Trejaut 2005-
Philippines0.00059Tajima 2004-
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Subclades

Haplogroup C, the most major one of three subclades is highly distributed among the Amerindian and Indigienous peoples of East Siberia. Haplogroup Z, the other one of three subclades is highly distributed among Even from Kamchatka (8/39 Z1a2a, 3/39 Z1a3, 11/39 = 28.2% Z total), mtDNA Haplogroup M8a, not well known one of three subclades is highly distributed among Northern Han Chinese from Liaoning (16/317 = 5.0%).

Tree

This phylogenetic tree of haplogroup M8 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[1] and subsequent published research.

  • M8
    • M8a
      • M8a1 - Ulch
        • M8a1a - Japanese
      • M8a2'3
        • M8a2 - Japanese, Han Chinese
        • M8a2-a* - Japanese, Russia
          • M8a2a'b (T152C!) - Japanese
            • M8a2a - Han Chinese
              • M8a2a1 - Japanese, Han Chinese(Hunan)
                • M8a2a1a1
              • M8a2a1b
              • M8a2a1c - Japanese
            • M8a2b - Japanese, Han Chinese (Shandong)
              • M8a2b1
              • M8a2b2 - Russia
          • M8a2c - Japanese, Han Chinese
          • M8a2d - Han Chinese
          • M8a2e - Ami(Taiwan Aborigines), Han Chinese (Taiwan)
        • M8a3 - Japanese, Han Chinese
          • M8a3a - Han Chinese
            • M8a3a1 - Han Chinese
    • CZ
      • C
        • C1
          • C1a - Ulch, Swedish
          • C1b - Amerindian
            • C1b1
            • C1b2
            • C1b3
            • C1b4
            • C1b5
              • C1b5a
              • C1b5b
            • C1b6
            • C1b7'10 (T16311C!)
              • C1b7
                • C1b7a
              • C1b10
            • C1b8
            • C1b9
            • C1b11
            • C1b12
            • C1b13
              • C1b13a
                • C1b13a1
              • C1b13b
              • C1b13c
                • C1b13c1
              • C1b13d
              • C1b13e
            • C1b14
          • C1c - Amerindian
            • C1c1
              • C1c1a
              • C1c1b
            • C1c2
            • C1c3
            • C1c4
            • C1c5
            • C1c6'7
              • C1c6
              • C1c7
            • C1c8
          • C1d - Amerindian
            • C1d1
              • C1d1a
                • C1d1a1
              • C1d1b
                • C1d1b1
              • C1d1c
                • C1d1c1
              • C1d1d
            • C1d2
              • C1d2a
            • C1d3
          • C1e - Amerindian
          • C1f - Amerindian
        • C4 - Siberian, Mongolian, Han Chinese
          • C4a'b'c
            • C4a
              • C4a1
                • C4a1a
                  • C4a1a1
                    • C4a1a1a
                  • C4a1a2'3'4
                    • C4a1a2
                      • C4a1a2a
                    • C4a1a3
                      • C4a1a3a
                        • C4a1a3a1
                      • C4a1a3b
                      • C4a1a3c
                      • C4a1a3d
                    • C4a1a4
                      • C4a1a4a
                  • C4a1a5
                  • C4a1a6
              • C4a2
                • C4a2a
                  • C4a2a1
                    • C4a2a1a
                    • C4a2a1b
                • C4a2b
                  • C4a2b1
                  • C4a2b2
                    • C4a2b2a
                • C4a2c
                  • C4a2c1
                  • C4a2c2
                    • C4a2c2a
            • C4b
              • C4b1
                • C4b1a
                • C4b1b
              • C4b2
                • C4b2a
              • C4b3
                • C4b3a
                  • C4b3a1
                • C4b3b
              • C4b5
              • C4b6
              • C4b7
              • C4b8
                • C4b8a
            • C4c
              • C4c1
                • C4c1a
                • C4c1b
              • C4c2
          • C4d'e
            • C4d
            • C4e
          • C5 - Siberian, Mongolian, Han Chinese
            • C5a
              • C5a1
              • C5a2
                • C5a2a
                • C5a2b
                  • C5a2b1
            • C5b
              • C5b1
                • C5b1a
                  • C5b1a1
                • C5b1b
                  • C5b1b1
            • C5c'd
              • C5c
                • C5c1
                  • C5c1a
              • C5d
                • C5d1
                • C5d2
          • C7 - Han Chinese, Indo-China Peninsulan
            • C7a
              • C7a1
                • C7a1a
                  • C7a1a1
                  • C7a1a2
                • C7a1c
                • C7a1d
              • C7a2
                • C7a2a
            • C7b
        • Z
          • Z1'2'3'4'7
            • Z1 - Tofalar
              • Z1a - Tubalar
                • Z1a1
                  • Z1a1a - Saami, Kets
                  • Z1a1b - Nganasan, Estonian
                • Z1a2 - Ulch
                  • Z1a2a - Nivkh
                • Z1a3 - Yakuts, Estonian
            • Z2 - Japanese
            • Z3 - Japanese
      • Z3a
        • Z3a1
          • Z3a1a - Han Chinese, Indian
        • Z3a2 - Indian
      • Z3b - Indian
        • Z3c - Persian(Iranian), Japanese
        • Z3d - Han Chinese, Taiwanese
            • Z4 - Han Chinese
              • Z4a - Japanese
                • Z4a1 - Han Chinese
                  • Z4a1a
                    • Z4a1a1 - Japanese
            • Z7 - Indian
          • Z5 - Japanese

The American figure skater Kristi Yamaguchi is a member of haplogroup M8a.[4]

See also

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T

References

Bibliography

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