Hayashi rearrangement

Chemical reaction From Wikipedia, the free encyclopedia

The Hayashi rearrangement is the chemical reaction of ortho-benzoylbenzoic acids catalyzed by sulfuric acid or phosphorus pentoxide.[1][2]

The Hayashi rearrangement
The Hayashi rearrangement

This reaction proceeds through electrophilic acylium ion attack with a spiro intermediate.[3][4]

Hayashi mechanism

References

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