Heme arginate

Heme arginate (or haem arginate) is a compound of heme and arginine used in the treatment of acute porphyrias.^[1][2] This heme product is only available outside the United States and is equivalent to hematin.^[3]

Quick facts Identifiers, Properties ...

Heme arginate

Identifiers
CAS Number	100438-92-4 Y
3D model (JSmol)	Interactive image
DrugBank	DB17310
MeSH	Heme+arginate
PubChem CID	3086464
UNII	R1B526117P N
InChI InChI=1S/C34H34N4O4.C6H14N4O2.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;7-4(5(11)12)2-1-3-10-6(8)9;/h7-8,13-16,35-36H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);4H,1-3,7H2,(H,11,12)(H4,8,9,10);/q;;+2/t;4-;/m.0./s1 Key: MGQITOFVXOEWNL-INZIHYEWSA-N
SMILES CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C=C.C(C[C@@H](C(=O)O)N)CN=C(N)N.[Fe+2]
Properties
Chemical formula	C40H48FeN8O6+2
Molar mass	792.704
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Close

Heme arginate is a heme compound, whereby L-arginine is added to prevent rapid degradation. It is given intravenously, and its action of mechanism is to reduce the overproduction of δ-aminolevulinic acid, which can cause the acute symptoms in an attack of the acute porphyrias.^[4]