Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
Class of enzymes
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Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (EC 2.5.1.83, HexPS, hexaprenyl pyrophosphate synthetase, hexaprenyl diphosphate synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 3 isopentenyl units).[1][2][3] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate 3 diphosphate + all-trans-hexaprenyl diphosphate
| Hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.83 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme prefers farnesyl diphosphate to geranylgeranyl diphosphate as an allylic substrate.
