Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific)
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Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) (EC 2.5.1.82, HexPS, (all-E) hexaprenyl diphosphate synthase, (all-trans) hexaprenyl diphosphate synthase, hexaprenyl pyrophosphate synthase, HexPPs, hexaprenyl diphosphate synthase) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transferase (adding 2 isopentenyl units).[1][2][3] This enzyme catalyses the following chemical reaction
- geranylgeranyl diphosphate + 2 isopentenyl diphosphate 2 diphosphate + all-trans-hexaprenyl diphosphate
| Hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.82 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme prefers geranylgeranyl diphosphate to farnesyl diphosphate as an allylic substrate.
