Hi1a
Peptide toxin from spiders
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Hi1a molecule is a peptide from the venom of Australian spider Hadronyche infensa (K’gari funnel web spider) which researchers have found, in studies done on mice, to be an acid-sensing ion channel 1a (ASIC1a) inhibitor.[1][2][3] It has cardioprotective properties - preventing heart tissue from degradation during a heart attack[2][4] and also has a highly neuroprotective effect in case of stroke.[5][6] It has the potential to become the first drug for acute ischemic events that act by preventing cell death.[1][3][7]