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Histamine trifluoromethyl toluidide

Chemical compound From Wikipedia, the free encyclopedia

Histamine trifluoromethyl toluidide (HTFMT) is a mixed H1/H2 histamine agonist which is significantly more potent than histamine itself.[1]

Quick facts Names, Identifiers ...
Histamine trifluoromethyl toluidide
Names
IUPAC name
6-[2-(1H-imidazol-5-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide
Other names
HTFMT, HTMT
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27) X markN
    Key: PMKJGGBYYNEYPA-UHFFFAOYSA-N X markN
  • InChI=1/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27)
    Key: PMKJGGBYYNEYPA-UHFFFAOYAA
  • FC(F)(F)c1ccc(cc1)NC(=O)CCCCC(NCCc2cnc[nH]2)C
Properties
C19H25F3N4O
Molar mass 382.42321
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It also produces additional actions which appear to be independent of histamine receptors.[2][3]

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