The oldest sign of human habitation in Hoczew is a gorod from the 9th and 10th centuries, found atop a hill near the confluence of the San and Hoczewka. Its location and size imply a defensive, and not residential, function. The first mention of Hoczew itself comes from 1400, when it was owned by the local judge in Sanok, Jaczek. In 1427, Hoczew and most of the lands around the Hoczewka became part of the property of Matiasz ze Zboisk, a local noble. He was the progenitor of the Bal family.[2]
The earliest church in Hoczew existed as early as 1424. In 1510, Mikołaj Bal, an official from Sanok, funded the construction of the first Church of Saint Anne. A small castle in Hoczew is mentioned in 1493. After Mikołaj's death, his sons, Matiasz III and Stanisław, converted to Calvinism. After the death of the previous parish priest, they did not allow a new priest to take charge in the parish of Hoczewka. By order of the bishop of Przemyśl, they were cursed, the Catholic Church's lands were retaken by the institution, and they were tried by a secular court, although not convicted of any offence.[2]
The Bals lost Hoczew in the early 17th century, following the marriage of Zofia Balówna with the voivode of Podolia, Stanisław Bełżecki. As of the early 18th century, it was owned by the Urbański family (the owners of Lutowiska), and from 1740 onwards, it was owned by the Fredro family. Their most notable member was the writer Aleksander Fredro.[2]
As of 1921, 848 people lived in the 144 homes of Hoczew. Of the 848 inhabitants, 470 were Greek Catholics, 310 were Roman Catholics, and 59 were Jews.[2]