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Hoehn and Yahr scale

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The Hoehn and Yahr scale is a commonly used system for describing how the symptoms of Parkinson's disease progress. It was originally published in 1967 in the journal Neurology by Margaret Hoehn and Melvin Yahr and included stages 1 through 5.[1] Since then, a modified Hoehn and Yahr scale was proposed with the addition of stages 1.5 and 2.5 to help describe the intermediate course of the disease.[2] It has been shown that HY stage discrimination can be automated, even with patients who cannot support themselves.[3]

More information Stage, Modified Hoehn and Yahr Scale ...
StageHoehn and Yahr ScaleModified Hoehn and Yahr Scale
1Unilateral involvement only usually with minimal or no functional disabilityUnilateral involvement only
1.5-Unilateral and axial involvement
2Bilateral or midline involvement without impairment of balanceBilateral involvement without impairment of balance
2.5-Mild bilateral disease with recovery on pull test
3Bilateral disease: mild to moderate disability with impaired postural reflexes; physically independentMild to moderate bilateral disease; some postural instability; physically independent
4Severely disabling disease; still able to walk or stand unassistedSevere disability; still able to walk or stand unassisted
5Confinement to bed or wheelchair unless aidedWheelchair bound or bedridden unless aided
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The scale is a subset of the Unified Parkinson's Disease Rating Scale, specifically the UPDRS V, allowing a more nuanced assessment of daily activities and non-motor symptoms in the context of disease therapy.[2]

Time between stages

A 2010 study of 695 patients (mean age: 65.2, male: 57.3%) found the median time taken to transit H&Y stages as shown below:[4]

More information Stage, Median Time to Transit (Months) ...
StageMedian Time to Transit (Months)
1-
220
2.562
325
424
526
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