Horsfiline
From Wikipedia, the free encyclopedia
| Names | |
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| Preferred IUPAC name
(3R)-5-Methoxy-1′-methylspiro[indole-3,3′-pyrrolidin]-2(1H)-one | |
| Identifiers | |
3D model (JSmol) |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C13H16N2O2 | |
| Molar mass | 232.283 g·mol−1 |
| Melting point | 125 to 126 °C (257 to 259 °F; 398 to 399 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba,[1] which is used in traditional herbal medicine. It has analgesic effects[medical citation needed] and has been the subject of research both to produce it synthetically by convenient routes[2][3][4][5][6][7][8] and to develop analogues and derivatives which may have improved analgesic effects.[9][10]
It is a member of the spiroindolone class. Elacomine has a similar chemical structure.
