Horsfiline

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Horsfiline
Names
Preferred IUPAC name
(3R)-5-Methoxy-1′-methylspiro[indole-3,3′-pyrrolidin]-2(1H)-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C13H16N2O2/c1-15-6-5-13(8-15)10-7-9(17-2)3-4-11(10)14-12(13)16/h3-4,7H,5-6,8H2,1-2H3,(H,14,16)/t13-/m0/s1 checkY
    Key: RVOLLKGLJIUGLG-ZDUSSCGKSA-N checkY
  • InChI=1/C13H16N2O2/c1-15-6-5-13(8-15)10-7-9(17-2)3-4-11(10)14-12(13)16/h3-4,7H,5-6,8H2,1-2H3,(H,14,16)/t13-/m0/s1
    Key: RVOLLKGLJIUGLG-ZDUSSCGKBT
  • O=C2Nc1c(cc(OC)cc1)[C@]23CN(C)CC3
Properties
C13H16N2O2
Molar mass 232.283 g·mol−1
Melting point 125 to 126 °C (257 to 259 °F; 398 to 399 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba,[1] which is used in traditional herbal medicine. It has analgesic effects[medical citation needed] and has been the subject of research both to produce it synthetically by convenient routes[2][3][4][5][6][7][8] and to develop analogues and derivatives which may have improved analgesic effects.[9][10]

It is a member of the spiroindolone class. Elacomine has a similar chemical structure.

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