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Hydrophilization

From Wikipedia, the free encyclopedia

Hydrophilization is a process used on hydrophobic drugs to increase their release rate from capsules, which depends on the rate of dissolution, by covering the surfaces of their particles with minute droplets of a dissolved hydrophilic polymer (such as methyl cellulose or hydroxyethyl cellulose).[1][2] In tablet or capsule formulations, this enhances the dissolution and disintegration of the drug.[2]

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