Hydrophosphonylation

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In chemistry hydrophosphonylation refers to any reaction where addition across a double bond generates a phosphonate (RP(O)(OR')2) group.[1] Examples include the Kabachnik–Fields reaction, where a dialkylphosphite reacts across an imine to form an aminophosphonate. The reaction is catalyzed by bases and is subject to organocatalysis.[2][3] Important compounds generated by this reaction include the common herbicide glyphosate.

Kabachnik-Fields Reaction

See also

References

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