ITM2C

ITM2C
Identifiers
Aliases	ITM2C, BRI3, BRICD2C, E25, E25C, ITM3, integral membrane protein 2C
External IDs	OMIM: 609554; MGI: 1927594; GeneCards: ITM2C
Gene location (Human)
Chr.	Chromosome 2 (human)
End	230,879,248 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	85,836,396 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; nucleus accumbens; ; anterior cingulate cortex; ; caudate nucleus; ; amygdala; ; external globus pallidus; ; rectum; ; prefrontal cortex; ; hypothalamus; ; putamen;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; nucleus of stria terminalis; ; supraoptic nucleus; ; entorhinal cortex; ; arcuate nucleus; ; CA3 field; ; lateral septal nucleus; ; median eminence; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	amyloid-beta binding; protein binding; ATP binding;
Cellular component	perinuclear region of cytoplasm; integral component of membrane; lysosomal membrane; extracellular exosome; membrane; lysosome; plasma membrane; Golgi apparatus;
Biological process	positive regulation of extrinsic apoptotic signaling pathway; negative regulation of neuron projection development; neuron differentiation; negative regulation of amyloid precursor protein biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	81618
	64294
	ENSG00000135916
	ENSMUSG00000026223
	Q9NQX7
	Q91VK4
	NM_030926; NM_001012514; NM_001012516; NM_001287240; NM_001287241
	NM_022417
	NP_001012532; NP_001012534; NP_001274169; NP_001274170; NP_112188
	NP_071862
	Wikidata
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