Iclazepam

Iclazepam
Identifiers
	IUPAC name 7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one;
CAS Number	57916-70-8 ;
PubChem CID	68777;
ChemSpider	62020 ;
UNII	FL061Q6NMC;
ChEMBL	ChEMBL2104257;
CompTox Dashboard (EPA)	DTXSID20206628 ;
Chemical and physical data
Formula	C21H21ClN2O2
Molar mass	368.86 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O;
	InChI InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2 ; Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N ;
	(verify)

Iclazepam (Clazepam) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide.

CAS Number

57916-70-8^Y

PubChem CID

68777

ChemSpider

62020^Y

UNII

FL061Q6NMC

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Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N¹ nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N-(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.^[1]

[1]

Iclazepam

See also

References

Related Articles

Identifiers

IUPAC name 7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
CAS Number	57916-70-8^Y
PubChem CID	68777
ChemSpider	62020^Y
UNII	FL061Q6NMC
ChEMBL	ChEMBL2104257
CompTox Dashboard (EPA)	DTXSID20206628
Chemical and physical data
Formula	C₂₁H₂₁ClN₂O₂
Molar mass	368.86 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O
InChI InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2^Y Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N^Y
(verify)