Idiopathic pneumonia syndrome

From Wikipedia, the free encyclopedia

SpecialtyPulmonology
CausesStem cell transplant
Idiopathic pneumonia syndrome
SpecialtyPulmonology
CausesStem cell transplant

Idiopathic pneumonia syndrome (IPS) is a set of pneumonia-like symptoms that occur with no sign of infection in the lung. Idiopathic pneumonia syndrome is a serious condition that occurs as a complication of a stem cell transplant.[1]

The symptoms are pneumonia-like, and include fever, chills, coughing, and breathing problems.[2]

Risk factors

IPS is a complication of a stem cell transplant. The incubation period ranges between 4 and 106 days, but mostly is about 22 days from transplant.[2]

Additional risk factors for IPS include total body irradiation dose, age, graft vs host disease, and multi organ failure.[2][1]

While older reports suggest a rate of as high as 15% of stem cell transplants resulting in IPS, recent studies suggest this is lowering.[3]

Diagnosis

Treatment

References

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