Imalumab

From Wikipedia, the free encyclopedia

Other namesBAX69
Legal status
  • Investigational
Imalumab
Monoclonal antibody
Type?
Clinical data
Other namesBAX69
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
UNII

Imalumab (BAX69) is an experimental monoclonal antibody against macrophage inhibitory factor (MIF), a cytokine known to exacerbate tumor growth.[1][2][3] and as of January 2017 it is being tested in Phase IIa clinical trials for metastatic colorectal cancer.[2] It was developed by Cytokine PharmaSciences and Baxalta, which was purchased by Shire Pharmaceuticals.[4]

A phase I/II trial in patients with malignant ascites was terminated in 2016.[4]

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