Indole-2-monooxygenase
Class of enzymes
From Wikipedia, the free encyclopedia
Indole-2-monooxygenase (EC 1.14.14.153, BX2 (gene), CYP71C4 (gene)) is an enzyme with systematic name indole,NAD(P)H:oxygen oxidoreductase (2-hydroxylating).[1] It catalyses the following chemical reaction:
| Indole-2-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.153 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Indole-2-monooxygenase is a cytochrome P450 protein containing heme, isolated from Poaceae (grasses). It uses molecular oxygen for the oxidation and requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate.[2] It is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.[3]
