Isabelle Le Callennec

Locally, Le Callennec was first a municipal councillor of Vitré (2008–2012) and a general councillor of Ille-et-Vilaine for the canton of Vitré-Est (2008–2015). When the General Council of Ille-et-Vilaine was renamed Departmental Council of Ille-et-Vilaine as part of the 2015 French cantonal reorganisation, she was elected for the newly created canton of Vitré for one term (until 2021). She later served as Mayor of Vitré from 2020 until her election as an MEP, presided over Vitré Communauté (2020–2024) and was elected to the Regional Council of Brittany in 2021.

In the 2016 The Republicans presidential primary, she supported François Fillon.^[3]

In the European Parliament, Le Callenec has been serving on the Committee on Regional Development and the Committee on Fisheries.^[4] In addition to her committee assignments, she is a member of the parliament's delegation to the EU-UK Parliamentary Partnership Assembly.^[5]

In the Republicans' 2025 leadership election, Le Callennec endorsed Laurent Wauquiez to succeed Éric Ciotti as the party's new chair and joined his campaign team.^[6]

As a deputy in 2013, Le Callennec opposed the legalisation of same-sex marriage in France.^[7] In 2014, she co-signed an amendment in the National Assembly proposing that abortion procedures no longer be reimbursed by Social security.^[8][9]