Isamide

Isamide, also known as N-chloroacetyl-5-methoxytryptamine, is a serotonin receptor antagonist and the N-chloroacetyl derivative of 5-methoxytryptamine.^[1][2][3] It was first described in the scientific literature by 1969 and was first pharmacologically characterized by 1979.^[4][2]

Other namesN-(1-Chloroacetyl)-5-methoxytryptamine

Drug classSerotonin receptor antagonist

CAS Number

• 21424-91-9

PubChem CID

• 192991

Quick facts Clinical data, Other names ...

Isamide

Clinical data
Other names	N-(1-Chloroacetyl)-5-methoxytryptamine
Drug class	Serotonin receptor antagonist
Identifiers
IUPAC name 2-chloro-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
CAS Number	21424-91-9
PubChem CID	192991
ChemSpider	167480
CompTox Dashboard (EPA)	DTXSID10175697
Chemical and physical data
Formula	C13H15ClN2O2
Molar mass	266.73 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC2=C(C=C1)NC=C2CCNC(=O)CCl
InChI InChI=1S/C13H15ClN2O2/c1-18-10-2-3-12-11(6-10)9(8-16-12)4-5-15-13(17)7-14/h2-3,6,8,16H,4-5,7H2,1H3,(H,15,17) Key:UCLPNTKRPMTACI-UHFFFAOYSA-N

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