Isoflavone 7-O-glucosyltransferase
Class of enzymes
From Wikipedia, the free encyclopedia
Isoflavone 7-O-glucosyltransferase (EC 2.4.1.170) is an enzyme that catalyzes several related chemical reaction that convert a phenolic hydroxy group in isoflavones to their glycosyl derivative.[1]
- UDP-glucose + an isoflavone UDP + an isoflavone 7-O-beta-D-glucoside
| isoflavone 7-O-glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.170 | ||||||||
| CAS no. | 97089-62-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The substrates of this enzyme are an isoflavone and UDP-glucose. These produce the corresponding isoflavone 7-O-beta-D-glucoside and the by-product uridine diphosphate (UDP). For example, daidzein is converted to daidzin.[2]
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase. Other names in common use include uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase, UDPglucose-favonoid 7-O-glucosyltransferase, and UDPglucose:isoflavone 7-O-glucosyltransferase. This enzyme participates in isoflavonoid biosynthesis.[1]
