JNJ-63533054

JNJ-63533054
Identifiers
	IUPAC name 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide;
CAS Number	1802326-66-4;
PubChem CID	2548547;
IUPHAR/BPS	8766;
ChemSpider	1896806;
ChEMBL	ChEMBL3633720;
PDB ligand	7ZQ (PDBe, RCSB PDB);
Chemical and physical data
Formula	C17H17ClN2O2
Molar mass	316.79 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H](C1=CC=CC=C1)NC(=O)CNC(=O)C2=CC(=CC=C2)Cl;
	InChI InChI=1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1; Key:MWDVCHRYCKXEBY-LBPRGKRZSA-N;

JNJ-63533054 is a chemical compound which acts as a small-molecule agonist of the previously orphan receptor GPR139.^[1]^[2]^[3] It has been used to investigate the role of GPR139 in various behavioral processes^[4] including sleep,^[5] anxiety,^[6] addiction,^[7] and cognition.^[8]

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Identifiers

IUPAC name 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
CAS Number	1802326-66-4
PubChem CID	2548547
IUPHAR/BPS	8766
ChemSpider	1896806
ChEMBL	ChEMBL3633720
PDB ligand	7ZQ (PDBe, RCSB PDB)
Chemical and physical data
Formula	C₁₇H₁₇ClN₂O₂
Molar mass	316.79 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C[C@@H](C1=CC=CC=C1)NC(=O)CNC(=O)C2=CC(=CC=C2)Cl
InChI InChI=1S/C17H17ClN2O2/c1-12(13-6-3-2-4-7-13)20-16(21)11-19-17(22)14-8-5-9-15(18)10-14/h2-10,12H,11H2,1H3,(H,19,22)(H,20,21)/t12-/m0/s1 Key:MWDVCHRYCKXEBY-LBPRGKRZSA-N

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