JUMPstart RNA motif
RNA family
From Wikipedia, the free encyclopedia
The JUMPstart RNA motif describes a conserved RNA-based secondary structure associated with JUMPstart elements.[1] The 39-base-pair JUMPstart sequence describes a conserved element upstream of genes that participate in polysaccharide synthesis.[2] The JUMPstart element has been shown to function as an RNA, and is present in the 5' untranslated regions of the genes it regulates.[3]
JUMPstart sequences include an ops element, which is an acronym for "operon-polarity suppressor" and has the nucleotide consensus GGCGGUAG.[4] The ops element acts in concert with the RfaH protein to improve transcription of genes downstream of the ops element, especially genes far away within long operons.[3][4][5][6]
