JYQ-42

Drug classSirtuin-6 (SIRT6) inhibitor

CAS Number

• 2838025-41-3

PubChem CID

• 175602516

FormulaC₁₃H₈ClF₃N₈O₂

JYQ-42

Clinical data
Drug class	Sirtuin-6 (SIRT6) inhibitor
Identifiers
IUPAC name 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-[3-chloro-5-(trifluoromethyl)phenyl]methylideneamino]triazole-4-carboxamide
CAS Number	2838025-41-3
PubChem CID	175602516
Chemical and physical data
Formula	C13H8ClF3N8O2
Molar mass	400.71 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=C(C=C(C=C1C(F)(F)F)Cl)/C=N/NC(=O)C2=CN(N=N2)C3=NON=C3N
InChI InChI=1S/C13H8ClF3N8O2/c14-8-2-6(1-7(3-8)13(15,16)17)4-19-21-12(26)9-5-25(24-20-9)11-10(18)22-27-23-11/h1-5H,(H2,18,22)(H,21,26)/b19-4+ Key:YUEMOICLRSWFIT-RMOCHZDMSA-N

JYQ-42 is a drug which acts as a sirtuin-6 (SIRT6) inhibitor. It has potential applications in cancer treatment, having been found to inhibit the migration of pancreatic cancer cells and thereby reduce tumor invasiveness.^[1][2]