Wyatt was born in Santa Monica to parents, Rhonda Knight and Mike, musicians she describes as "hippies", who gave her the middle name Wyatt after Wyatt Earp.[3] Her great-grandparents played country music and her uncle was a champion fiddle player.[4] Her father grew up in an Irish-Catholic family; her grandmother was from Dublin.[1] Wyatt grew up in Fox Island, Washington, in what she describes as "the woods".[5] She grew up going to mass every week.[5] She has two older sisters,[5] horseback riders whereas she was interested in skateboarding.[6][5] Her parents divorced when she was age 10. She lost contact with her father while her mother struggled financially as a single parent.[6][5] She went to concerts often; her first was Bonnie Raitt, whom her dad knew. Her father was also friends with Bobby Weir.[6] She played little league and was the only girl on the team.[5] She self-identifies as "part Cherokee", stating that her family moved from Oklahoma to California.[7]
In 2002, at age 17, shortly after high school, she was discovered by producer Skip Williamson, who moved her to Los Angeles and signed her to his Lakeshore Records.[6][3][8]
On Lakeshore, in 2004, she released a self-titled EP produced by Pete Droge. Songs from the EP were featured in the films: Wicker Park (2004), The Midnight Meat Train (2008), and Feast of Love (2007). One song, "Mind Candy" was re-recorded by Tiffany Darwish.[8]
In January 2017, she released "Your Loving Saves Me", featuring Sam Outlaw.[4]
In February 2017, Wyatt debuted her first album Felony Blues with Forty Below Records. The songs address topics including her crime, addiction, depression, and recovery.[9]
In March 2018, Wyatt was featured on the song "Skinny Elvis" by Sam Morrow.[10]
In February 2020, Wyatt released Neon Cross, produced by Shooter Jennings.[11]
Wyatt is featured on the song "Bring It Home" by Dropkick Murphys, released in May 2023.
In November 2023, Wyatt released Feel Good, her third studio album, on New West Records.
