James Brydges, 3rd Duke of Chandos

Chandos was Member of Parliament for Winchester from 1754 to 1761 and for Radnorshire between 1761 and 1768.^[2] He succeeded in the dukedom upon the death of his father on 28 November 1771.

He was a Gentleman of the Bedchamber to George, Prince of Wales from 1760 to 1764, the Lord Lieutenant of Hampshire in 1763–64 and 1771–80, sworn to the Privy Council on 12 May 1775 and appointed Lord Steward of the Household from December 1783 to his death in 1789.^[3]

Chandos's first marriage was to Margaret Nicol (1736–1768), daughter of John Nicol of Colney Hatch and Minchenden House, and his wife Winifred Keck, on 22 March 1753. They set up a London home at 39 Upper Grosvenor Street, Mayfair.^[4] Margaret inherited much of the great fortune acquired by her grandfather Sir Anthony Keck, and was the owner of a famous portrait of Shakespeare, which came to be known as the Chandos portrait following the marriage.

A decade after the death of his first wife, and having become Duke of Chandos in 1771, he married Anne Eliza Gamon, daughter of Richard Gamon of Datchworth Bury, Datchworth, on 21 June 1777. This second marriage produced the only child to survive to adulthood, Lady Anne Elizabeth Brydges (Lady Kinloss, died 1836)^[2] who married Richard Temple-Grenville, 1st Duke of Buckingham and Chandos. They were the parents of Richard Temple-Nugent-Brydges-Chandos-Grenville, 2nd Duke of Buckingham and Chandos.

Chandos died in September 1789, aged 57, when the Dukedom became extinct. He was buried in St Lawrence Whitchurch in Canons Park, London.^[5] His widow was declared a lunatic and confined to their London home, Chandos House; after her death in 1813, the unexpired lease was sold. She was also made a ward of court. There was a lengthy lawsuit in the Irish Courts over the management of her property. In 1794 judge Richard Power, accountant-general and usher of the Court of Chancery, was accused of misappropriating some of the duchess's income and died in a presumed suicide.