She is Consultant in Intensive Care Medicine and Anaesthesia and Joint Group Medical Director at the Manchester Royal Infirmary. She also serves as Clinical Chair of the Greater Manchester Critical Care Operational Delivery Network, and member, Faculty Board for Intensive Care Medicine.[2] She is Chair, Oversight Board, Manchester Rare Conditions Centre.[3]
She has developed guidelines to respond to acute illness of adults in hospital.[4] The guidelines recognised that patients in hospital are at risk of becoming ill due to the complexity of their conditions, comorbidities and age. If managed inappropriately, deteriorating health in hospital can compromise referral to critical care, and even result in unnecessary death.[4] She suggested that critical care teams should write a clear, written monitoring plan to document the diagnosis, potential comorbidities and treatment plan.[4]
During the COVID-19 pandemic she helped to deliver the Manchester Hospital Trust pandemic response plan.[5][6][7] During the infected blood scandal Eddleston gave evidence on behalf of the Manchester Royal Infirmary.[8]
In 2022 she was awarded the Faculty of Intensive Care Medicine Gold Medal.[1] Her award citation read, “many working in intensive care medicine today have been influenced by her and many patients and services have benefited from her vision and drive for improvement,”.[5] Under her leadership, Greater Manchester were awarded funding for health research that delivers earlier and more accurate detection, diagnosis and prognosis of disease.[9][10]