On October 1, 1988, Sellers flirted with a no-hitter through 7+1⁄3 innings until Luis Medina of the Cleveland Indians hit a home run accounting for the only run in a 1–0 victory over the Red Sox. Sellers struck out 10 Cleveland batters in the losing effort, which turned out to be his last major league appearance.[3]
Before the 1989 season, Sellers, Todd Benzinger, and a minor leaguer were sent by Boston to the Cincinnati Reds in the same transaction that brought Nick Esasky and Rob Murphy to the Red Sox. But Sellers suffered an injury the following spring and did not play in MLB for the Reds.[4] He went on to play in the minor league systems of the Reds, New York Yankees, Texas Rangers and Colorado Rockies before retiring for good after the 1994 season.[2]