John Keith Moffat
Biophysicist
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John 'Keith' Moffat (born 1943) is Louis Block Professor of Biochemistry and Molecular Biology and former Deputy Provost for Research at the University of Chicago.[3][4] He currently heads BioCARS at Argonne National Laboratory, where he worked on the Advanced Photon Source.[3][5] He is most noted for his contributions to Time resolved crystallography.[6][7] He is a former Guggenheim Fellow and former Cornell University faculty member.[4] He has a Ph.D. from King's College, Cambridge under the Nobel laureate Max Perutz at MRC-LMB and an undergraduate degree from the University of Edinburgh.[8][9] He is married with an adopted son.[3]
Born1943 (age 82–83)
EmployerUniversity of Chicago
John Keith Moffat | |
|---|---|
| Born | 1943 (age 82–83) |
| Occupations | Professor; former Deputy Provost |
| Employer | University of Chicago |
| Scientific career | |
| Education | University of Edinburgh King's College, Cambridge |
| Known for | Time resolved crystallography |
| Awards | Guggenheim Fellowship |
| Fields | Biophysics |
| Workplaces | University of Chicago Cornell University |
| Max Perutz | |
Other academic advisors | Quentin Gibson[1] |
Notable students | Werner G. Krebs[2] |
| Website | biophysics |
Selected publications
- Srajer, V.; Teng, T.-y.; Ursby, T.; Pradervand, C.; Ren, Z.; Adachi, S.-i.; Schildkamp, W.; Bourgeois, D.; Wulff, M.; Moffat, K. (1996). "Photolysis of the Carbon Monoxide Complex of Myoglobin: Nanosecond Time-Resolved Crystallography". Science. 274 (5293): 1726–9. Bibcode:1996Sci...274.1726S. doi:10.1126/science.274.5293.1726. PMID 8939867. S2CID 35873469.
- Crosson, S.; Moffat, K. (2001). "Structure of a flavin-binding plant photoreceptor domain: Insights into light-mediated signal transduction". Proceedings of the National Academy of Sciences. 98 (6): 2995–3000. Bibcode:2001PNAS...98.2995C. doi:10.1073/pnas.051520298. PMC 30595. PMID 11248020.
- Genick, U. K.; Borgstahl, G. E.; Ng, K; Ren, Z; Pradervand, C; Burke, P. M.; Srajer, V; Teng, T. Y.; Schildkamp, W; McRee, D. E.; Moffat, K; Getzoff, E. D. (1997). "Structure of a Protein Photocycle Intermediate by Millisecond Time-Resolved Crystallography". Science. 275 (5305): 1471–5. doi:10.1126/science.275.5305.1471. PMID 9045611. S2CID 20434371.
- Crosson, Sean; Rajagopal, Sudarshan; Moffat, Keith (2003). "The LOV Domain Family: Photoresponsive Signaling Modules Coupled to Diverse Output Domains†". Biochemistry. 42 (1): 2–10. doi:10.1021/bi026978l. PMID 12515534.
- Crosson, S.; Moffat, Keith (2002). "Photoexcited Structure of a Plant Photoreceptor Domain Reveals a Light-Driven Molecular Switch". The Plant Cell Online. 14 (5): 1067–1075. doi:10.1105/tpc.010475. PMC 150607. PMID 12034897.