Wright became a consultant in clinical epidemiology at Bradford Royal Infirmary in 1996 and authored three books on health needs assessment, global public health and clinical governance. In 2004 he was appointed Director of Research.
He established the Born in Bradford longitudinal birth cohort study in 2006. The study recruited almost 14,000 mothers and their partners in pregnancy and has followed the lives of 13,500 children born in the city between 2007 and 2011.[6][7]
In January 2022, plans were unveiled by Wright to build on this study by launching a new health research project called Age of Wonder with the aim of tracking more than 30,000 adolescents on their journey into adulthood.[8][9] The seven-year study was backed by a £7m grant from the Wellcome Trust.
He leads the ActEarly City Collaboratory programme, funded by the Medical Research Council to develop ways to improve the health and life chances of children living in deprived communities.[10]
He established the Bradford Institute for Health Research in 2007, uniting NHS organisations and the University of Bradford, University of Leeds and University of York to develop a centre for applied health research. In 2019 he established the Wolfson Centre for Applied Health Research.[11]
He set up the Yorkshire and Humber Improvement Academy in 2013 to support the translation of research evidence into clinical practice. In 2017 he established the Connected Bradford programme[12] to safely and securely link health, education, environmental and social care data for over 600,000 citizens.
He has run an international health partnership with Good Shepherd Hospital in the Lubombo region of Swaziland for over 25 years. In 2002, the link-up benefited from a donation 31 from the Foundation set up by the British singer, pianist and composer Sir Elton John to help fight AIDS.[13] In 2021, he was instrumental in launching City of Research, a new initiative to encourage more volunteers from across Bradford, Airedale and Craven to sign up to take part in health research.[14][15]
He is also a strong advocate of the new Clean Air Zone being introduced across Bradford[16][17] Under his leadership, Bradford was recognized as a leading research-recruiting hospital in England for the first time in 2024.[18]