del Río has served as the secretary for the Vox party in Cordoba. Ahead of the April 2019 Spanish general election, he stood as a candidate for the party in the Cordoba constituency and was elected to the Congress of Deputies. He was again re-elected in November 2019.[4][5]
In politics, del Río has focused on matters related to education. In the Congress, he sits on the committees for Culture and Education.[6] He also supports keeping the borders with Ceuta and Melilla between Morocco closed and has accused the Moroccan government of violating Spanish territorial waters.[7] In line with Vox's policy stance, he also favours ending public subsidies to NGOs and movements which seek to promote regional separatism in Spain and signed a letter with other Vox representatives calling on Spaniards to "defend the homeland against separatism."[8] In 2019, del Río went against Vox's policy which called for the removal of a bust of Abd al-Rahman III in a public square in the town of Cadrete by arguing that "judging past events from the present is absurd." Local politicians from the People's Party and Citizens had also supported the removal of the bust.[9]