KDM3A
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Lysine demethylase 3A is a protein that in humans is encoded by the KDM3A gene.[5]
External IDsOMIM: 611512; MGI: 98847; HomoloGene: 10196; GeneCards: KDM3A; OMA:KDM3A - orthologs
Function
This gene encodes a zinc finger protein that contains a jumonji C (JmjC) domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants. KDM3A catalyzes the demethylation of H3K9me1 and H3K9me2 residues. Its function is dependent on the presence of cofactors Fe(II) and α-Ketoglutarate.[6]