KLF10

KLF10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EPA
Identifiers
Aliases	KLF10, EGR-alpha, EGRA, TIEG, TIEG1, Kruppel-like factor 10, Kruppel like factor 10
External IDs	OMIM: 601878; MGI: 1101353; HomoloGene: 4135; GeneCards: KLF10; OMA:KLF10 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	102,655,725 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	38,300,950 bp
RNA expression pattern
	Top expressed in
	mucosa of paranasal sinus; ; skin of hip; ; skin of thigh; ; germinal epithelium; ; gastric mucosa; ; synovial joint; ; parietal pleura; ; saphenous vein; ; lactiferous duct; ; human penis;
	Top expressed in
	spermatocyte; ; gastrula; ; urothelium; ; urinary bladder; ; transitional epithelium of urinary bladder; ; left lung lobe; ; renal corpuscle; ; stria vascularis; ; muscle of thigh; ; plantaris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; metal ion binding; protein binding; nucleic acid binding; core promoter sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	skeletal system development; bone mineralization; cellular response to peptide; regulation of transcription, DNA-templated; somatic stem cell population maintenance; rhythmic process; cell-cell signaling; positive regulation of osteoclast differentiation; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; circadian rhythm; cell population proliferation; transforming growth factor beta receptor signaling pathway; negative regulation of cell population proliferation; cellular response to starvation; regulation of circadian rhythm; negative regulation of transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7071
	21847
	ENSG00000155090
	ENSMUSG00000037465
	Q13118
	O89091
	NM_001032282; NM_005655
	NM_001289471; NM_013692; NM_001357677
	NP_001027453; NP_005646
	NP_001276400; NP_038720; NP_001344606
	Wikidata
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