KRT32

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.^[5][6][7][8]

AliasesKRT32, HA2, HKA2, KRTHA2, hHa2, keratin 32

External IDsOMIM: 602760; MGI: 1309995; HomoloGene: 68246; GeneCards: KRT32; OMA:KRT32 - orthologs

Chr.Chromosome 17 (human)^[1]

End41,467,386 bp^[1]

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KRT32
Identifiers
Aliases	KRT32, HA2, HKA2, KRTHA2, hHa2, keratin 32
External IDs	OMIM: 602760; MGI: 1309995; HomoloGene: 68246; GeneCards: KRT32; OMA:KRT32 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17q21.2 Start 41,459,513 bp[1] End 41,467,386 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 D|11 63.4 cM Start 99,971,674 bp[2] End 99,979,052 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in hair follicle skin of arm periodontal fiber nipple human penis skin of abdomen skin of leg vagina pharynx cervix Top expressed in lip esophagus superior surface of tongue hair follicle Ileal epithelium skin of back morula urethra skin of abdomen extensor digitorum longus muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity Cellular component intermediate filament extracellular exosome cytosol Biological process epidermis development keratinization cornification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3882 16670 Ensembl ENSG00000108759 ENSMUSG00000046095 UniProt Q14532 Q62168 RefSeq (mRNA) NM_002278 NM_001159374 NM_010665 RefSeq (protein) NP_002269 NP_001152846 Location (UCSC) Chr 17: 41.46 – 41.47 Mb Chr 11: 99.97 – 99.98 Mb PubMed search [3] [4]
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The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.^[8]